IBanga le-1421373-66-1 i-Mesylate-AZD9291 yoNyango lweCancer

Inkcazelo emfutshane:

Ubunyulu:≧99%, Mhlophe ukuya kokukhanya komgubo oqinileyo otyheli

Umgangatho Womgangatho:Endlwini okanye njengoko kufuneka

Isatifikethi:I-COA.I-MOA, i-MSDS, njl

Umthamo:50Kgs/ngenyanga

Beka ubomi kwishelufa:Iminyaka emi-3

Isicelo:I-EGFR tyrosine kinase inhibitors (EGFR TKI)

Iqela eliluncedo:Iqela lokuthengisa impahla ngaphandle elinamava kunye noqeqesho lobungcali kumzi-mveliso

Thumela i-imeyile kuthi Khuphela njengePDF

Iinkcukacha zeMveliso

FAQ

Iithegi zeMveliso

Imvelisoigama	AZD-9291 mesylate
Izithethantonye	N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]- I-2-propenamide methanesulfonate (1:1)
Inombolo yeCAS.	1421373-66-1
Imbonakalo	Umgubo oqinileyo omhlophe ukuya kumthubi
Ifomula yeemolekyuli	C₂₈H₃₃N₇O₂.CH₄O₃S
Ubunzima beMolekyuli	595.71
Ukusetyenziswa	IBanga lezamayeza okanye injongo yoPhando
Ukupakisha	Ngokwesicelo sakho
Ugcino	Londoloza kwizikhongozeli eziqinile, ezikwaziyo ukumelana nokukhanya kwindawo epholileyo

AZD-9291 mesylateCAS:1421373-66-1
Iixesha	Simigangatho	Riziphumo
Imbonakalo	Umgubo oqinileyo omhlophe ukuya kumthubi	Umgubo oqinileyo otyheli
Iukuchongwa	Ngu-IR	Iyahambelana
Iukuchongwa	Nge-HPLC	Iyahambelana
Ukunyibilika	Inyibilika kwi-Dimethylsulfoxide, inyibilika kancinane kwi-Ethanol kunye ne-Acetonitrile, kunye ne-pH exhomekeke ekunyibilikeni kwamanzi.	Iyahambelana
Isiqulatho samanzi(KF)	≤ 1.00%	0.42%
Intsalela kwi-Ignition	≤ 0.10%	0.05%
HlulaMokqhubekayo	≤ 20ppm	Iyahambelana
Mesylate	15.20%~18.20%	15.90%
Izinyibilikisi ezishiyekileyo	I-acetonitrile: ≤410ppm	ND
	I-acetone: ≤5000ppm	ND
	I-Tetrahydrofuran: ≤720ppm	ND
RndivuyaSizinto	Ubuninzi bokungcola okukodwa: ≤0.20%	0.17%
RndivuyaSizinto	Ukungcola okupheleleyo: ≤1.00%	0.25%
Ubungakanani beNcam	D90: ≤100μm	57.97%
Athetha (isiseko se-HPLC ekomisweni)	98.00%~102.00%	99.80%
Umgangatho weReferensi	Umgangatho wangaphakathi wendlu

Ulwazi lweNkampani

√ Amava apheleleyo omaleko wolawulo kumzi-mveliso kunye namagcisa anezakhono abalandeli;
√ Umgangatho usoloko uyingqwalasela yethu ephezulu, inkqubo yeQC eQinisekileyo;
√ Iminyaka eli-11 yamava eqela lokuthengisa kumazwe angaphandle;
√ ilebhu yeR&D eZimeleyo;
√ Iindibano zocweyo zeGMP ezimbini ezityikityiweyo zexesha elide;
√ Imithombo etyebileyo yeefektri ezininzi ezingasebenziyo ukulungiselela iprojekthi elungelelanisiweyo;
√ Iqela elisebenzayo eliSebenzayo ngokuSebenzayo ngendlela engaguqukiyo.
imgsaf